Abstract
Effect of gossypol and its mono-derivatives (monoamigossypol, monoaminogossypol) on ion transport across mitochondria membrane was investigated. Comparison investigation of influence of gossypol and its derivatives to transfer of protons through membrane shows different activities. However, gossypol has the highest activity than its derivatives. Mitochondrial permeability transition pore mPTP in vitro activities of gossypol and its derivatives were investigated too. Comparison results were the same.
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