Abstract

The decline of health-related quality-of-life (QOL) during the year after radical prostatectomy is severe. General self-efficacy (GSE) is an effective psychological factor for long-term regulation of patient behavior and emotions. GSE is expected to facilitate enhanced health-related quality of life. We evaluated changes in GSE and analyzed the relationship between GSE and prostate cancer-specific and general health-related QOL. We conducted a longitudinal survey with 104 patients who underwent radical prostatectomy and administered the General Self-efficacy Scale (GSES), Expanded Prostate Cancer Index Composite (EPIC), and SF8 Health Survey (SF-8). ANCOVA was performed to compare EPIC and SF-8 between GSES high and low-medium groups. GSES scores increased significantly after 6months. Regarding EPIC urinary summary scores, high GSES group was significantly higher than low-medium group at 1month (mean score difference [MSD], 7.3; 95% CI 1.1-13.2, P = 0.016), 3months (MSD, 6.8; 95% CI 0.7-12.8, P = 0.028), and 6months (MSD, 6.3; 95% CI 0.9-11.7, P = 0.022). High GSES group had significantly higher SF-8 physical component summary score at 6months (MSD, 3.2; 95% CI 1.4-5.0, P = 0.001), and significantly higher SF-8 mental component summary score at 1month (MSD, 2.6; 95% CI 0.4-4.9, P = 0.022), 3months (MSD, 2.7; 95% CI 0.8-4.6, P = 0.007), and 6months (MSD, 2.8; 95% CI 1.0-4.6, P = 0.003). This study suggests that high GSE was associated with better prostate cancer-specific and general health-related QOL after radical prostatectomy.

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