Effect of Gender on Some Biochemical Parameters in Iraqi Cholelithiasis patients.

Abstract

Gallstones (GS) are abnormal solid lumps of a mixture of cholesterol crystals, mucin, calcium bilirubin, it is the most common problems affecting the digestive tract, the present study enable us to classify the studied gallstone patients into gallstone patients without any complication (cholelithiasis) . The aim of the current study is to evaluate the level of the xanthine oxidase(XO) and dehydrogenase(XDH) activity, and several biochemical factors in sera of cholelithiasis patients according to the gender (male and female). Thirty-five of cholelithiasis patients were male and forty-one were female, for comparison, apparently fifty-seven healthy were enrolled as control; twenty-nine of them were male and twenty-eight were female. The age of these groups ranged from 41 to 50years.The resultswere appeared that XO activity and its specific activity(S.A.XO) were significantly increase in female patient groups when compared to male and female patient groups, on the other hand the mean levels of XDH activity and S.A.XDH showed high significant decreases, that's mean female gender is the highlights and proven risk factor for gallstone formation.