Abstract
AbstractThe effect of ganglionic blocking on piasma renin activity and plasma sodium concentration during exercise and pain stress were studied in rats. 20 female albino rats were exercised by swimming and 16 received intramuscular injections of 1 ml 10% NaCl. Half of the animals in each group were pretreated with a ganglionic blocking drug (Ansolysen®). In both groups there was a significantly lower plasma renin activity in the ganglion‐blocked animals compared with their untreated controls, which indicates the importance of the sympathetic system for renin release. The findings suggest that changes in plasma sodium concentration are of minor importance compared with sympathetic activity.
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