Effect of Fractional Carbon Dioxide Laser vs Sham Treatment on Symptom Severity in Women With Postmenopausal Vaginal Symptoms: A Randomized Clinical Trial

Abstract

(Abstracted from JAMA 2021;326:1381–1389) An estimated 40% to 60% of women experience vaginal symptoms associated with menopause, which can lead to physical discomfort, as well as negatively affecting sexual function, relationships, and quality of life. Preliminary data have shown that fractional laser treatments used as nonhormonal alternatives for postmenopausal vaginal symptoms result in improvement in vaginal atrophy after treatment.