Abstract
The study investigated the effects of FMD vaccination on acute phase response and milk composition in the HF crossbred cows (n = 12) using a cross-over experimental design. In trial 1, one group (n = 6) received inactivated trivalent oil-adjuvanted FMD vaccine [day post-vaccination, (dpv) 0], while the mock-vaccinated group received saline (n = 6). After a cooling period of 15 days, the trial was repeated by swapping groups. The body temperature, dry matter intake (DMI) and milk yield were recorded. Haemato-biochemical parameters, haptoglobin and cortisol concentrations were also assessed. A significant (p < 0.05) increase in the neutralizing antibody response to FMDV serotype O and Asia1 indicated a positive immune response. A significant (p < 0.05) increase of 0.4° to 0.6°C in the body temperature, decrease of 0.7–0.8 kg in DMI along with an increase in the serum haptoglobin, total leukocyte count and neutrophils within dpv 2 indicated acute phase response in the FMD vaccinated group. Among the milk constituents, only milk fat (p = 0.053) was significant. It was concluded that FMD vaccination induced acute phase response within dpv 3 in the crossbred cows and caused a non-significant reduction in the milk yield on the day of vaccination.
Published Version (
Free)
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
