Abstract

Objective To observe the effect and the possible mechanism of foot reflexology and music therapy on cancer pain intervention.Methods 90 Patients were randomly divided into 3 groups:normal therapy,palma reflexology massage; palma reflexology massage plus music therapy,30 patients in each group.Evaluated pain score by changhai pain rating scale,and tested patients' peripheral plasma concentration of β-endorphin、prostaglandin E2 and epinephrine by ELISA.Results Patients' pain score reduced to varying degrees,but no statistical differences were found among three groups with regard to pain score and serum concentration of β-endorphin,prostaglandin E2 and epinephrine 3 days post intervention (P > 0.05 ).the pain score was (4.21 ± 0.67 ),(2.12 ± 1.39 ) and ( 1.88 ± 0.77) respectively in normal therapy group,palma reflexology massage group and palma reflexology massage plus music therapy group ( F =21.99,P < 0.05 ),Statistical differences were found between 3 days and 6 days post intervention among internal palma reflexology massage and palma reflexology massage plus music therapy separately with regard to serum concentration of prostaglandin E2 and epinephrine ( P < 0.05 ),whereas no statistical differences were found be tween the two groups at the two time points (P > 0.05 ).Conclusions Palma reflexology massage can alleviate cancer pain; its mechanism may be due to its psychological effects,stimulating the modulation effect of meridians and collaterals,modifying pain-related cytokines secretion. Key words: Cancer pain; Palma reflexology massage; Music therapy; Mechanism

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