Abstract
The effectiveness of adhesive restorations depends on a durable long-term dentin bond. Due to collagen fibril denaturation, the consistency and durability of bonding to caries-affected dentin can be questioned as compared to sound dentin. Exogenous cross-linking agents have been suggested as a viable method of inhibiting MMP activity and retaining collagen within the dentin-bonded interface. Due to their strong antioxidant capacity, flavonoids are natural cross linkers that play an important role in protecting unprotected collagen fibrils inside the hybrid layer. This study aimed to evaluate the effectiveness of flavonoids incorporated dentin adhesives in improving the bond strength of composite resin. A search was performed in the electronic databases (PUBMED CENTRAL, Medline, Scopus, Lilacs, Science Direct, Google scholar and Hand Search) using search terms alone and in combination by means of PUBMED search builder upto March 2021. Also cross check of reference was done on all potentially eligible articles. Initially 47 articles were identified.2 articles were removed because of duplicates. After title and abstract screening 27 articles were removed.After reading full texts,4 articles were removed and finally 14 articles were included in this review for detailed analysis.
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