Abstract
HE FIRST DAY graft nonfunction has been recognized to be one of the most important risk factors of the short and long term graft survival rates in cadaveric renal transplantation. ‘J It is defined by inadequate urine output and need for dialysis in the immediate posttransplant days. Using the United Network for Organ Sharing (UNOS) database, Terasaki and coworkers have shown that the effect of first-day diuresis is more important than HLA matching in cadaveric renal allograft survival rates.3 Again, according to their findings, the survival rate of grafts mismatched for all six HLA antigens but functioning on the first day was higher than that of a perfectly matched graft that did not function immediately. As a large number of living related (LRD) and living unrelated donor (LUD) renal transplantations have been performed in our center in last 10 years the aim of this study was to determine: (1) the frequency and causes of first-day renal allograft nonfunction and (2) the effect of first-day graft nonfunction on short- and long-term graft survival rates in our LRD and LUD transplantations.
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