Effect of Fibre-Enriched Orange Juice on Postprandial Glycaemic Response and Satiety in Healthy Individuals: An Acute, Randomised, Placebo-Controlled, Double-Blind, Crossover Study.

Neus Bosch-Sierra,Aránzazu Gurrea-Martínez,Carlos Bald,Antonio Hernández-Mijares,Clara Talens,Saioa Alvarez-Sabatel,Roger Marqués-Cardete,Carlos Morillas,Celia Bañuls,Carmen Grau-Del Valle

doi:10.3390/nu11123014

Abstract

Background: Consumption of fibre-enriched orange juice may be an appropriate way to supplement daily fibre intake and achieve beneficial effects on metabolic health. The present study aimed to assess the short-term effects of fibre-enriched orange juice on postprandial metabolism and satiety in a healthy adult population. Methods: In this double-blind, randomised, placebo-controlled, crossover study 10 healthy subjects underwent two one-day trials in which they consumed an orange juice beverage containing 1.4 g/100 mL of citrus fibre (29.3% soluble and 41.9% insoluble) or a placebo (regular orange juice without added fibre). Postprandial glucose, insulin, gut hormones (GLP1, GIP and ghrelin), leptin and qualitative appetite/satiety assessment were measured every 15 or 30 min over the 120 min test period. Results: The fibre-enriched orange juice decreased postprandial serum glucose and circulating insulin levels at 15 min compared with the placebo. In addition, after intake of the fibre-enriched juice, a significant effect on qualitative feelings of satiety and fullness was observed at 15 and 120 min, and was accompanied by a significant decrease in GLP1 response at 15 min. No significant changes were observed in leptin, GIP and ghrelin after juice intake. Conclusions: In healthy individuals, a single acute consumption of fibre-enriched orange juice has short-term beneficial effects on postprandial glycaemia, circulating insulin levels and satiety through GLP1 secretion.

Highlights

Dietary fibre is the edible portion of plant-derived foods that are resistant to enzymatic digestion and absorption in the gut [1]
We have proved that large amounts of fibre (> 5 g fibre per serving) are not required to observe a significant effect on satiety and postprandial glycaemic response in healthy subjects but probably are needed to trigger a significant reduction of both glucose and insulin
Our findings demonstrate the beneficial effect-in the initial phase of absorption-of a single acute dose of fibre-enriched orange juice on glucose and insulin levels in healthy individuals with normal weight compared with a placebo

Summary

Introduction

Dietary fibre is the edible portion of plant-derived foods that are resistant to enzymatic digestion and absorption in the gut [1]. The average intake of dietary fibre is lower than recommended, at around 20 g/day in the European population [3], due to a low consumption of fruits, vegetables, legumes and cereals In this context, fibre supplements added to the regular diet could be the key to achieving the recommended intake. The effect on the feeling of satiety can vary depending on the physicochemical properties (hydration, viscosity, particle size, fermentability) and type of fibre, and this can have an impact on the caloric intake of individuals. In this way, fibre contributes substantially to energy balance [4]. No significant changes were observed in leptin, GIP and ghrelin after juice intake

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Results

Discussion

Conclusion