Abstract
Treatment with small quantities of fetal tissue from randomly bred Sprague—Dawley rats can either potentiate or depress the development of DMBA-induced breast tumors in young adult female Holtzman rats. The difference between potentiation and suppression of tumors depended upon whether the fetal tissue had been killed (by freeze—thawing and homogenization), which potentiated tumor development, or whether a viable mince of fetal tissue had been used, which greatly suppressed tumor development and caused a high rate of tumor regression.
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