Abstract

Holtzman rat dams were maintained on a liquid diet containing 35% ethanol-derived calories from Days 5 to 18 of gestation. Beginning on Day 19, the dams were given 5 days of choice between the ethanol diet and lab chow and water, which allowed the animals to decrease their alcohol consumption slowly. 9 male offspring of the ethanol-treated dams were compared to 9 male offspring of pair-fed dams on the acquisition of a LRRL sequence in a four-choice maze, with training beginning at 116 days of age. While the alcohol group had higher means on all acquisition measures and higher variances on all error measures, the group means were not significantly different on any of the acquisition measures.

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