Abstract

The effect of fenithrotion (FS) on the functionality of two models of crustacean lipoproteins was studied. Models used were a high density plasma lipoprotein (HDL) that is involved in the lipid–tissue exchange, and a lipovitellin (LV), the main source of embryo nutrients, which presents two forms only distinguishable in its lipid composition. The relative influence of lipid and apoprotein compositions on the FS effect in lipid transfer was comparatively evaluated using liposomes prepared with lipids obtained from both lipoproteins. FS treatment of HDL modified the transfer of lipids to and from hepatopancreas, diminishing the uptake of phosphatidylcholine and triacylglycerols and increasing its capacity to release both lipids to the tissue. Likewise, FS increased the transfer of phophatidylcholine to the embryonic tissue from both LVs and from liposomes. It was assessed that apoproteins are involved in the transfer of phosphatidylcholine to tissues, though they are not involved in the changes produced by FS concerning the affinity of this lipid to lipoprotein systems.

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