Abstract
-1. Blood glucose and lactate levels were comparable in fed rats and guinea-pigs but blood alanine was three times higher in rats than in guinea-pigs. 2. After a 48 hr fasting period blood concentration and turnover rates of glucose, lactate and alanine decreased in rats. 3. After a 48 hr fasting period blood concentration and turnover rates of glucose and lactate did not vary in guinea-pigs whereas blood alanine and alanine turnover increased. 4. Increased availability of glucose precursors and a better efficiency of gluconeogenic processes in fasted guinea-pigs compared to fasted rats may explain in part the different variation of blood glucose and glucose turnover rate during starvation in the two species.
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