Effect of fast track surgery on gastrointestinal function and stress response in patients with colorectal cancer after minimally invasive treatment

Abstract

Objective To explore the effect of fast track surgery (FTS) on gastrointestinal function and stress response after minimally invasive treatment of colorectal cancer patients. Methods 110 cases of colorectal cancer who were treated with laparoscopic surgery from January 2014 to June 2017 were collected. The patients were divided into the fast track surgery group (group FTS) and the non fast track surgery group (non FTS group) according to the perioperative treatment. In this study, SPSS 24 statistical software package was used for statistical analysis. The measurement data is expressed by ±s, compared with t test. The repeated measurements of IL-6, CRP and TNF-α were compared by repeated measurements of variance. The number of complications, such as the incidence of complications, was expressed by n(%), and compared with chi square test. The study was statistically significant with the difference of P<0.05. Results The postoperative exhaust time, defecation time, postoperative hospitalization time and hospitalization cost in group FTS were significantly lower than those in the non FTS group (P 0.05). There was no significant difference in IL-6 and TNF-α between the two groups after 7 days of treatment. The IL-6, CRP and TNF-α in the FTS group at the rest of the time were significantly lower than those in the non FTS group. There was no significant difference in the incidence of complication between the two groups after operation (P>0.05). Conclusion The intervention of FTS can ignificantlys reduce the stress response of the patients with colorectal cancer after minimally invasive treatment, accelerate the gastrointestinal function recovery of the patient, reduce postoperative hospital stay time and patients’ hospitalization expenses, which is worthy of clinical promotion. Key words: Colorectal Neoplasms; Laparoscopy; Gastrointestinal Motility; Fast Track Surgery