Abstract


 
 
 
 Purpose: To investigate the therapeutic effect of fallopian tube dredging using a combination of hysteroscopy and Traditional Chinese Medicine (TCM) containing marine-derived bioactive principles on patients with inflammatory obstruction of fallopian tube.
 Methods: A total of 108 patients with inflammatory obstruction of fallopian tube admitted to Weifang Maternal and Child Health Hospital from February 2017 to February 2018 were enrolled in the study. The patients were randomized into study group (n = 54) and reference group (n = 54). The reference group received traditional laparotomy, while the study group received fallopian tube dredging using hysteroscopy in combination with TCM containing marine-based bioactive principles. The clinical effects of the two treatments were compared.
 Results: The number of completely unobstructed patients was significantly higher in the study group than in the reference group, with lower number of patients unilaterally unobstructed in the study group (p < 0.05). No significant differences in the number of bilaterally obstructed patients between the two groups were observed (p > 0.05). The study group showed an evidently higher total effectiveness rate than the reference group (p < 0.05). Stronger evidence of a higher number of cases of intrauterine pregnancy in the study group than that in the reference group was found, while a strikingly lower number of pregnancy failures and ectopic gestations in the study group was obtained, when compared to the reference group (p < 0.05).
 Conclusion: Fallopian tube dredging combined with hysteroscopy and TCM containing marine-derived principles effectively improves treatment outcomes in patients with fallopian tube obstruction. Thus, the combination therapy has greater benefits than the traditional approach.
 
 
 

Highlights

  • The prevailing rapid pace of modern life has resulted in increased prevalence of infertility [1,2]

  • Fallopian tube dredging with hysteroscopy is the primary treatment for inflammatory obstruction of fallopian tube, which has been appreciated by its rapid dredging of obstructed tubes, maintenance of unobstructed tubes, and safety and thoroughness of the operation

  • Traditional Chinese Medicine (TCM) containing formulas derived from marine microorganisms belongs to the category of natural drugs that can reduce the adverse effects of drugs on patients [6,7]

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Summary

Introduction

The prevailing rapid pace of modern life has resulted in increased prevalence of infertility [1,2]. Fallopian tube dredging with hysteroscopy is the primary treatment for inflammatory obstruction of fallopian tube, which has been appreciated by its rapid dredging of obstructed tubes, maintenance of unobstructed tubes, and safety and thoroughness of the operation. Traditional Chinese Medicine (TCM) containing formulas derived from marine microorganisms belongs to the category of natural drugs that can reduce the adverse effects of drugs on patients [6,7]. The present study was carried out to investigate the therapeutic effect of fallopian tube dredging with combination of hysteroscopy and TCM containing marine microorganism-derived bioactive principles on patients with inflammatory obstruction of fallopian tube. Clinical data of 108 patients with inflammatory obstruction of fallopian tube admitted to our hospital from February 2017 to February 2018 were retrospectively analyzed

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