Abstract

Bilateral extirpation of the superior cervial sympathetic ganglia during the first months of life in young rats caused retardation in growth by 40–60%. Division of preganglionic sympathetic fibers and mock operations produced no significant changes. Normal growth and development of the skeleton were disturbed in the ganglionectomized rats: the zone of growth of the proximal end of the tibia in the ganglionectomized animals was much narrower than in the intact controls and delay in the spread of secondary centers of ossification was observed.

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