Abstract

The pattern of RNA synthesis during status epilepticus was studied in the cerebral extrafocal cortex of cats. The results indicated a change in the pattern of RNA synthesis suggesting an inadequate processing of precursor RNA molecules into mature products. The newly synthesized cytoplasmic RNA was composed of discrete species whereas the corresponding RNA of the controls showed a heterogeneous distribution. Such discrete species might be involved in cellular processes of particular importance in this functional state.

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