Abstract
Summary Introduction Irisin myokine whose secretion is induced by exercise is associated with an increase in thermogenesis. However, the effect of acute and chronic exercise on the production and release of irisin in overweight individuals is controversial. Objective To evaluate whether acute and chronic exercise affects irisin concentrations in overweight individuals. Methods The Medline/PubMed and Science Direct databases were used. The data search included clinical trials with humans that assessed the effect of acute or chronic exercise on irisin concentrations in overweight or obese individuals. The search terms used were: “irisin” AND “exercise” OR “acute exercise” OR chronic exercise “OR” endurance exercise “OR” aerobic exercise “OR” strength exercise “OR” resistance exercise “OR” obesity”. Results Nine articles performed in healthy and diabetic subjects were found. The irisin concentrations in individuals with excess weight increased with acute exercise and remained the same with chronic exercise. The maximum concentration of irisin occurred between 1 and 2 hours after the exercise was completed. The protocols of resistance and high-intensity training were more effective. Conclusion The increase in irisin concentrations after exercise is transient. Further research is needed to assess whether this change has a cumulative effect and actually acts on thermogenesis.
Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
