Abstract
9583 Background: Changes in cognitive function are reported in 15-75% of individuals during or following cancer treatment. Currently, there is little available evidence of effective intervention strategies to address this issue. However, exercise presents a potentially effective intervention, as improvements in cognitive function with exercise have been demonstrated in other populations. However, to date there have been no published randomized controlled trials examining the effect of exercise on cognitive function in cancer survivors. Methods: A proof-of-concept randomized controlled trial (RCT) in women, treated for breast cancer within the past 3 years, who self-report persistent cognitive dysfunction following chemotherapy treatment (n=20). Participants were randomized to a 24-week aerobic exercise intervention or delayed exercise control. The primary outcome was self-reported cognitive function and impact on quality of life (QoL), using the FACT-CoG. The secondary outcome was performance on a standar...
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