Abstract
An enkephalin-like tetrapeptide (subcutaneous, intraperitoneal and intraventricular injections) disturbs the goal-oriented food instrumental behavior of rats by decreasing the number of adequately performed instrumental reactions. In addition to these disorders, intraventricular microinjections entail an increase in the number of inadequate, incomplete behavioral reactions. Besides, injection of the tetrapeptide evokes specific disorders of motor activity, which manifest in the occurrence in rats of stretches, "duck-like step", motor stereotypy, arching of the tail, changes in the tone of abdominal muscles, etc. The tetrapeptide effects described were not inhibited by narcan, remaining unchanged for 3.5-5 months following a single injection of the tetrapeptide.
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