Abstract
To observe the effect of electroacupuncture (EA) combined with general anesthesia for the immune function of patients treated with laparoscopic radical rectectomy for rectal cancer. Fifty patients who would receive selective laparoscopic radical rectectomy for rectal cancer with general anesthesia were randomly divided into an observation group and a control group,25 cases in each one. Fifteen minutes before anesthesia induction,patients in the observation group were treated with EA at Zusanli (ST 36) and Sanyinjiao (SP 6) until the end of operation. Sham acupuncture without piercing the skin was applied at the same acupoints in the control group, and electrodes were connected without stimulation. Interferon-γ (IFN-γ), interleukin-4 (IL-4), interleukin-6 (IL-6) were quantitatively tested before anesthesia (T0), at the time of abdomen closing (T1) and one hour after anesthesia anabiosis (T2). And serum procalcitonin (PCT) level, leucocyte count and the number of cases with increasing leucocyte (the standard number>10×109/L) were measured on the first day after operation. The levels of IL-4 and IL-6 were increased apparently and the ratio of IFN-γ/IL-4 was decreased at T2 compared with those before treatment in the control group (all P<0.05), but obvious change did not appear in the observation group (all P>0.05). The ratio of IFN-γ/IL-4 was enhanced (P<0.05),and the levels of IL-4 and IL-6 were reduced (both P<0.05) at T2 in the observation group compared with those in the control group. The level of PCT of the observation group was markedly lower than that of the control group on the first day after operation (P<0.05). There was no statistical significance about leucocyte count and the number of cases with increasing leucocyte between the two groups (both P>0.05). EA at Zusanli (ST 36) and Sanyinjiao (SP 6) could alleviate the depressing immune function and inflammatory reaction of patients after laparoscopic radical rectectomy for rectal cancer.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callMore From: Zhongguo zhen jiu = Chinese acupuncture & moxibustion
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
