Abstract
Background and Aims: Among the changes found during atherosclerosis, a phenotypic switch of the vascular smooth muscle cells (vSMC) represents one of the key elements in the development and/or progression of the disease. The role of bioactive elastin-derived peptides (EDPs) and carbamylation in the development and the evolution of atheroma has been highlighted in the past few years but the combination of these two phenomena remains to be explored. The aim of this work is to study the effect of EDPs and carbamylated-EDPs on the phenotype of vSMCs.
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