Effect of elastic band resistance training with green coffee extract supplementation on adiposity indices and TyG-related Indicators in Obese Women

Abstract

Green coffee supplementation has demonstrated beneficial anti-inflammatory and anti-obesity effects. Accordingly, we examined the effects of a green coffee (GC) extract concurrent to elastic band resistance training (EBRT) on insulin resistance, adiposity indices [Visceral (VAI), Body (BAI)] TyG-related indicators (TyG-BMI and TyG-WC) in obese women. Obese participants (N = 60, 30-50 y, BMI >30 kg/m 2 ) were randomized equally into a randomized, double-blind, placebo-controlled trial (Zhang et al., 2014) Placebo (PLA), (Rahmani et al., 2015) PLA+ Resistance training, (Yaghoobi et al., 2015) PLA+R, (Blüher, 2019) GC, GC+Resistance training (GC+R). Treatment capsules contained 500 mg of GC and 50% chlorogenic acid (250 mg) for 8-wks. Resistance training consisted of 3 sessions per/wk/60-min. Paired-sample t -test and two-factor ANOVA were used for within and between-group comparisons. We observed a significant pre/post reduction for HOMA-IR (Primary Outcome; mean (SD) for the PLA+R (3.67 ± 0.70 vs. 3.22 ± 0.74 mg/dL) and GC+R (3.88 ± 0.54 vs. 3.21 ± 0.61, both p < 0.001), but not GC 3.79 ± 0.77 vs. 3.54 ± 0.71, P = 0.058) and PLA 3.41 ± 0.76 vs. 3.69 ± 0.95, P = 0.21). Both GC+R (P = 0.005) and PLA+R were significant vs. PLA (P = 0.011). Secondary outcomes included a significant reduction in glucose for PLA+R (94.61 ± 8.12 vs. 89.08 ± 9.70 mg/dL) and GC+R (94.36 ± 10.67 vs. 84.5 ± 11.02 mg/dL, both P < 0.001), but not GC (94.07 ± 7.39 vs. 91.79 ± 8.50 mg/dL, P = 0.07) and PLA (91.46 ± 10.28 vs. 99.92 ± 20.12 mg/dL, P = 0.053). Both GC+R (P = 0.002) and PLA+R were significantly different (P = 0.019) vs. PLA. Finally, Apo A-I significantly improved for GC+R compared vs. PLA, P = 0.033) and BAI significantly improved for. PLA+R (P = 0.021), GC+R (P = 0.006) and GC vs. PLA. Despite no synergistic exercise and green coffee treatment effects, exercise improved most TyG parameters and lipid profiles in obese women. • No synergistic exercise and green coffee treatment effects on Adiposity Indices and TyG-related Indicators in Obese Women. • Elastic-band resistance training improved TyG parameters and lipid profile in line with the improvement in body composition. • Green coffee supplementation only improves body composition but not blood sugar levels and insulin resistance.