Abstract
The synthesis of biocompatible hydrogel based on poly (ethylene glycol) (PEG) and ethylene diamine (EDA) using epoxy-amine chemistry was conducted. PEG was chosen as the base material (or monomer) to synthesise hydrogels in this study due to its high hydrophilicity, biocompatibility and low toxicity properties. The effects of mole ratios of EDA to PEGDGE on the hydrogel scaffolds properties (i.e., gelling time, swelling) were investigated. It was found out for hydrogel scaffolds prepared at 1.2 and 1.4 M [PEGDG and an EDA/PEGDGE mol ratio of 0.5 in DMSO gave the optimum hydrogel properties. Swelling studies has confirmed that hydrogel prepared at 0.5 mole ratios consist of highly cross-linked network as expected.
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