Abstract

An early dysphoric response following treatment with antipsychotic medication may lead to discontinuation of antipsychotic medication and thereby to relapse and rehospitalisation. Also cannabis use has found to be related to non-adherence to therapy. In the present study we examined whether 1) an early dysphoric response to antipsychotic medication, 2) cannabis use were related to discontinuation of antipsychotic medication in patients with early psychosis, and 3) whether there were differences in discontinuation between olanzapine compared with risperidone.

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