Effect of Dvi-Avartita Bhringaraja Taila in Dushtha Vrana (Chronic Infected Ulcer)

Abstract

Dushtha vrana (chronic infected ulcer) was mentioned as one of the types of Vrana (wound/ ulcer). Sushruta in his Sushruta samhita, a representative treatise of Indian school of surgery, devoted many chapters for the description and management of Vrana. According to modern medicine and recent researches the etiology and pathogenesis of wound and its healing involves many systemic, local, and molecular factors. Foreign bodies, tissue maceration, ischaemia, infection, systemic factors like advanced age, malnutrition, diabetes, and renal disease are some among them. Ayurveda advocates both internal and external therapies for the management of Vrana. Upward and downward evacuation, fasting, de-saturating diet, blood letting, washing of the wound with medicated decoctions, external application of medicated oils etc. are some among them. Though many factors involves in wound healing, the complex interaction between epidermal and dermal cells and the extra cellular matrix are considered to play an important role. Based on this fact and in order to simplify the treatment, as per the classical references Dvi-avartita Bhringaraja taila was selected for the present study. Fifteen patients of chronic infected ulcers of variant etiology with common features like ulcer with foetid pus, oozing, pain etc. were selected for the present study. Out of 15 cases, 8 (53.33%) got good response, 5 (33.33%) got fair response, 1 (6.67%) got poor response and 1 (6.67%) case had no response. Parameter wise 80.00% of relief in pain, 73.17% in curing of Pus discharge, 81.08% in curing of Foul smell, 78.79% relief in Oedema/ induration and 65.00% Reduction of ulcer were found. Over all 69.52% relief was found by assessing all parameters. Statistical analysis of the mean difference before and after treatment in relief on all the above symptoms were found highly significant (P<0.0001).