Effect of dry body weight on intra-dialytic hypertension in patients on regular hemodialysis

Abstract

Background: In chronic kidney disease, hypertension is influenced by both blood pressure (BP) and the progression of renal disease. In end stage renal disease (ESRD) on maintenance hemodialysis, hypertension is a main feature and more than 85% of new patients with ESRD present with hypertension. The aim of this study: was to assess the relationship between dry body weight and intra-dialytic hypertension in patients on regular hemodialysis. Patients and Methods: This was an observational cohort study with retrospective data analysis including (age and sex matched) patients with end stage renal disease. The study will be conducted in Nephrology Unit national institute of nephrology &urology. Results: there was statistically significant difference found between the two studied groups regarding LL edema, Sacral edema, Pl. effusion, Increased cardio/thoracic ratio, and Increased IVC diameter with (p-value= 0.016, 0.027, 0.019, 0.003 and 0.008) respectively. Conclusion: IDH is preventable if we control modifiable risk factors such as, reducing interdialytic weight gain, correction of serum albumin and urea reduction ratio. This will reduce cardiovascular morbidity and mortality in CKD patients on maintenance hemodialysis.