Effect of Drotaverine administration on cervical dilatation in uncomplicated deliveries

Abstract

Background: Prolonged labour can lead to increased maternal and neonatal mortality and morbidities. Active management of labour versus physiological, expectant management has shown to decrease the occurrence of prolonged labour. Administering antispasmodics during labour could lead to faster and more effective dilatation of the cervix. Objective: To know the effect of Drotaverine on dilatation of cervix in uncomplicated deliveries compared to the data obtained in patients without smooth muscle relaxants METHODS: This study was conducted on 200 cases of uncomplicated pregnancies. 100 cases in study group and 100 cases in control group who fulfilled the relevant criteria were admitted in department of OBG in Government Medical College-Nizamabad-Telangana. Cases in study group were given 40mg of Drotaverine IM, when cervix was 3cms dilated and then labour was monitored using partogram. Second dose of Drotaverine was given 2 hrs after the first dose depending on progress of labour. RESULTS: The average duration of dilatation stage was 4 hours and 10 minutes (250mins) in primigravida of study group while it was 6 hours and 30 minutes (390min) in control group. The average duration of dilatation stage was 3 hours (180min) in second gravida in study group, while it was 4hrs 30 min (270min) in control group CONCLUSION: Intramuscular administration of Drotaverine injection in dilatation phase of uncomplicated pregnancies was found to reduce the duration of cervical dilatation, total duration of labour, and incidence of cervical tears with no change in stage 2 and 3 of labour.