Abstract
AbstractPromazine derivative (PZD) photosensitization is known to induce loss of bacteriophage infectivity (Merville et al., 1983). Since one of the primary events in replication of DNA viruses is DNA transcription, studies were undertaken in order to investigate the effects of DNA-PZD photosensitization on this transcription. SV40-DNA FI was chosen because under definite temperature conditions (18°C) and under a definite RNA polymerase (E.coli)-DNA molar ratio(1.5) one specific initiation site of transcription is used on the SV40 genome (Reisbig & Hearst, 1981).
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Schedule a callMore From: Archives Internationales de Physiologie et de Biochimie
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