Abstract
We investigated the effect of rubbing the DNA‐Na from salmon milt on human skin condition. A 3% DNA‐Na cream or the control cream was rubbed onto the male subjects (ten/group) for 12 weeks. The results showed that the DNA cream improved skin‐elasticity more than the control cream after the fourth week. The change in skin‐elasticity was improved significantly. Rubbing of the DNA cream tended to decrease transepithelial water loss (TEWL) and to increase water content in the face skin at 12 weeks. In addition, according to the results of a questionnaire, more than 90% of the subjects who used the DNA cream felt improving roughness of the skin. In conclusion, these results showed that their skin conditions were improved by rubbing on the DNA‐Na. We evaluated the promoting effect of the DNA‐Na on the production of hyaluronic acid using human normal dermal fibroblasts. The results showed that the DNA‐Na has the promoting effect of hyaluronic acid production on the fibroblasts. This data suggested that the DNA‐Na would improve skin conditions.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
