Abstract
FFORTS by the authors2 to eliminate pleuropneumonialike organisms (PPLO) from eggs by treating infected hens failed to corroborate reports of successful results by others. The possibility that fertile hens' eggs infected with PPLO might be treated effectively by immersing them in antibiotic solutions appeared to be a more promising approach in the control of chronic respiratory disease (CRD). At the instigation of the senior author, three laboratory trials were done wherein moderate or small PPLO inoculums injected into the fresh yolk of uninfected fertile eggs previously dipped in antibiotics, failed to grow when the yolks were cultured after three weeks of incubation. The untreated eggs and the eggs with the heavier inoculums did yield the organism on culture.1 These encouraging results prompted further laboratory and field studies.
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