Abstract

Tissue gas levels were measured in experimental skin flaps in rabbits, rats, and pigs. Devascularization of the flaps led to a fall in PO2 and a rise in PCO2 levels. Application of DMSO to ischemic rabbit flaps led to a fall in PCO2, DMSO and H2O2 led to a rise in PO2, an effect that lasted up to 90 min. Neither drug had an effect on the gas levels of flaps in either rats or pigs.

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