Abstract

Continuous production of l-ornithine by an arginine auxotroph of Brevibacterium ketoglutamicum was carried out in a 2- l jar fermentor. The effects of the dilution rate on the fermentation parameters were investigated under l-arginine limited conditions. The maximum l-ornithine yield and volumetric productivity obtained were 0.213 g/g and 0.313 g/ l/h, respectively. The specific l-ornithine production rate increased with the dilution rate, with a maximum value of 0.084 g/g/h at a dilution rate of 0.125 h −1.

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