Effect of Different Wavelengths of Laser Irradiation on the Skin Cells.

Aleksandra Cios,Łukasz Szymański,Martyna Ciepielak,Sławomir Lewicki,Mariola Mendrycka,Aneta Lewicka,Wanda Stankiewicz,Szczepan Cierniak

doi:10.3390/ijms22052437

Abstract

The invention of systems enabling the emission of waves of a certain length and intensity has revolutionized many areas of life, including medicine. Currently, the use of devices emitting laser light is not only an indispensable but also a necessary element of many diagnostic procedures. It also contributed to the development of new techniques for the treatment of diseases that are difficult to heal. The use of lasers in industry and medicine may be associated with a higher incidence of excessive radiation exposure, which can lead to injury to the body. The most exposed to laser irradiation is the skin tissue. The low dose laser irradiation is currently used for the treatment of various skin diseases. Therefore appropriate knowledge of the effects of lasers irradiation on the dermal cells’ metabolism is necessary. Here we present current knowledge on the clinical and molecular effects of irradiation of different wavelengths of light (ultraviolet (UV), blue, green, red, and infrared (IR) on the dermal cells.

Highlights

Lasers (Light Amplification by Stimulated Emission of Radiation) are widely used tools in science, medicine, and industry
Effective treatment of laser observed in the head, folds, back, abdomen and limbs (6 weeks observation)
PASI score lowered after laser treatment (6 weeks observation)

Summary

Introduction

Lasers (Light Amplification by Stimulated Emission of Radiation) are widely used tools in science, medicine, and industry. The most popular application of lasers is as a cutting tool. The third popular application of lasers is the treatment of various diseases (medicine) or correction of the inaccuracies of the body (cosmetology). It determines the depth of the penetration by the light—the higher the wavelength, the greater the laser penetration through the tissues [9]. This is associated with the thermal effect caused by the light which increases with the increasing wavelength. The parameters are the density of the laser energy, and the duration of radiation. We describe the mechanisms of action of ultraviolet (UV), blue, green, red, and infrared (IR) lasers on the cells cultured in vitro, and the treatment of skin diseases

Lasers and LEDs

Laser Interaction with a Skin

Main Findings after Laser Treatment

Main Findings normal human fibroblasts

Main Findings

Conclusions