Effect of Different Selenium Sources on Antioxidant Enzymes and Bioavailability in Goats

Abstract

To assess the antioxidant effect of selenium (Se) yeast and sodium selenite, 18 non-descript male kids (2–3 months old, 6.63±0.24 kg body weight) were divided into three groups (6 each) following completely randomized design. Animals in the control group (T1) were fed concentrate mixture and oat straw ad libitum, while animals in T2 and T3 were additionally supplemented with 0.30 mg selenium/kg of diet through Se yeast and sodium selenite, respectively. RBC GSH-Px activity was significantly (P<0.05) higher in T2 and T3 as compared to T1. CAT activity of erythrocytes increased significantly (P<0.05) in T2 and T3 kids compared to control kids. Malonaldehyde (MDA) values were significantly (P<0.05) lower in T2 and T3 as compared to control. The SOD enzyme activity was significantly (P<0.05) higher in kids supplemented with organic Se compared to other groups The mean Se levels in serum of kid at 180 days of the experiment were 210, 330 and 265 ppb in T1, T2 and T3 groups, respectively. It was found that supplementation of selenium both in organic and inorganic form significantly (P<0.05) increased antioxidant enzymes activity and Se bioavailability in goats, organic Se was more effective than inorganic Se.