Abstract
The aim of this study was to examine the effect of running exercise modality on oxidative stress. Thirteen endurance athletes (age: 21.46 ± 0.66 years) performed three different running exercise modalities (Continuous running exercise (CR): continuous running exercise at 75% of VO2max for 25 min; intermittent running exercise #1 (15/15): intermittent running protocol, 15 s running at 75% of VO2max, 15 s passive recovery, performed for 50 min; intermittent running exercise #2 (30/30): intermittent running protocol, 30 s running at 75% of VO2max, 30 s passive recovery, performed for 50 min) in a randomized order. Blood samples were drawn at rest and immediately after each running exercise and assessed for malondialdehyde (MDA), advanced oxidation protein products (AOPP), superoxide dismutase(SOD), and glutathione peroxidase (GPX) activities. MDA increased by 55% following 30/30 exercise (p < 0.01), while it remained unchanged with CR and15/15 exercise. SOD increased after CR (+13.9%, p < 0.05), and also remained unchanged after 15/15 (p > 0.05) and decreased after 30/30 (−19.7% p < 0.05). GPX and AOPP did not change after exercise in all experimental sessions (p > 0.05). In conclusion, 30/30 intermittent running induced higher lipid damages than the 15/15 and CR exercise. 15/15 intermittent exercise promoted a better balance between free radicals production and antioxidant defense compared to continuous exercise and intermittent 30/30 exercise.
Highlights
The practice of regular physical activity [1] and running [2] are recognized as essential factors for maintaining good health [1]
The aim of the might presenthave study was to analyze the effects of different runningstress exercise modalities different running exercise modalities, which may improve the prescription of running training by on antioxidant and free radical damages in male athletes
The aim of the present study was to determine the effect of running exercise modality on oxidative stress biomarkers
Summary
The practice of regular physical activity [1] and running [2] are recognized as essential factors for maintaining good health (e.g., fighting against cardiovascular diseases, osteoarthritis, diabetes, and osteoporosis) [1]. The practice of long and/or intense physical exercise can expose athletes to muscle injuries and chronic fatigue, which can be directly linked to the toxic effects of free radicals (FR) [3]. Res. Public Health 2020, 17, 3729; doi:10.3390/ijerph17103729 www.mdpi.com/journal/ijerph
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
