Abstract
目的 探讨超声乳化白内障手术不同切口对术后泪膜变化的影响.方法 行白内障超声乳化吸除术的非干眼患者54例(60眼),年龄为54～78岁.随机分为两组:A组28例(30眼),行透明角膜切口;B组26例(30眼),行巩膜隧道切口.两组的年龄、性别等差异无统计学意义,具有可比性.分别于术前,术后第1天、第7天、第14天、第30天、第90天对患者行干眼主观症状问卷调查、基础泪液分泌试验(Schirmer I test,SIt)、泪膜破裂时间(break-up time,BUT)和角膜荧光素染色(cornea fluorescein staining,CFS)检查.采用SPSS 10.0统计软件,对数据进行卡方检验和t检验分析.结果 ①主观症状:术后第1天和第7天,患者干眼主观症状明显,B组干眼症状评分大于A组,差异有统计学意义(t=-6.208,-2.868;P 0.05).②Slt试验:术后第1天,SIt明显增加,B组Sit较A组长,差异有统计学意义(t=-2.916;P 0.05).⑨BUT:术后第1天、第7天、第14天.BUT明显缩短,B组BUT较A组长,差异有统计学意义(t=-3.719,-2.442,-2.507;P 0.05).(CFS评分:术后第1天、第7天、第14天,CFS评分增加,A组CFS评分大于B组,差异有统计学意义(t=3.478,3.261,2.466;P 0.05).结论 术后早期,行巩膜隧道切口超声乳化白内障吸除术对泪膜稳定性的影响较小,但干眼症状重于行透明角膜切口的患者.术后晚期,两种切口对泪膜的影响无明显差异。
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