Effect of different crystalloid preload volumes combined with prophylactic norepinephrine infusion on inferior vena cava collapsibility index and post-spinal anesthesia hypotension during cesarean section: a randomized controlled trial

Abstract

Vasopressor and fluid administration are important strategies to prevent and treat post-spinal anesthesia hypotension at cesarean section.1–2 As a principalstrategy, vasopressors, especially α-adrenergic agonists, are used to counteract decreases in peripheral vascular resistance induced by sympathetic blockade.3 The inferior vena cava (IVC) collapsibility index (CI) is a useful measure with which to estimate cardiac preload and volume status.4 In this study we investigated the effect of different crystalloid preload volumes combined with prophylactic norepinephrine infusion on IVC-CI and post-spinal anesthesia hypotension in patients undergoing cesarean section.