Abstract
BackgroundPrevious studies have shown beneficial effects of dietary approaches for iron deficiency anemia (IDA) control. This study was design to investigate the effect of dietary intervention treatment on children with iron deficiency anemia.MethodsWe performed a systematic review of published dietary interventions effect on IDA treatment through meta-analysis. CBM, CNKI, Wanfang database, EMBASE, VIP, PubMed and Web of science database were searched to identify studies published between January, 1980 and December, 2016. Statistical analysis was performed by Revmen5.2 software.ResultsInitially we retrieved for 373 studies, and then 6 studies with a total of 676 individuals were included in the analysis according to the inclusion and exclusion criteria for meta-analysis. The overall pooled estimate of odds ratio [(OR), 95% confidence intervals (95% CI)] in the dietary intervention on children with iron deficiency anemia was 6.54 (95% CI: 3.48-12.31, Z = 5.82, p<0.001) and funnel plot is symmetric.ConclusionsOur meta-analysis suggested that dietary interventions are effective in improving the iron deficiency in children with iron deficiency anemia (IDA) and should be considered in the overall strategy of IDA management.
Highlights
Previous studies have shown beneficial effects of dietary approaches for iron deficiency anemia (IDA) control
Our present meta-analysis about the effect of dietary intervention on children with iron deficiency anemia established that dietary intervention had a beneficial effect on children with IDA, as supported by significantly increase effect of dietary intervention (OR = 5.03, 95% Confidence intervals (CI): 3.09- 8.18)
Results from subgroup analysis indicated odds ratio (OR) of 4 weeks intervention is higher. This may be ascribed to the short time, so that children with iron deficiency anemia can’t recover completely
Summary
Previous studies have shown beneficial effects of dietary approaches for iron deficiency anemia (IDA) control. This study was design to investigate the effect of dietary intervention treatment on children with iron deficiency anemia. Iron deficiency anemia (IDA) is an anemia caused by a lack of iron which is a most common and widespread nutritional disorders among infants and children in the world in under-developing countries [1]. It has been estimated that prevalence of IDA is very high in India (60% to 80%) than anywhere else in the world [2–6]. The prevalence of IDA is varying from 10 to 40% in P. Young children are at high risk for iron deficiency anemia due to their high dietary iron requirements. It has already been highlighted that IDA has a significant impact
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