Effect of dietary garlic supplementation on lipid peroxidation and protein oxidation biomarkers of tissues as well as some serum biochemical parameters in common carp Cyprinus carpio

Abstract

This study aims to investigate the effects of dietary garlic powder (25 and 50 g kg−1 feed) supplementation for 6 weeks on lipid and protein oxidation biomarkers in various tissues as well as some blood biochemical parameters in common carp. Based on the present study results, serum malondialdehyde (MDA) concentrations were decreased following garlic supplementation, but the decrease was only significant (P < 0.05) in the group that received 50 g kg−1 dietary garlic compared with the control group. Moreover, garlic at 50 g kg−1 diet caused significant decrease in MDA values of liver and kidney. Additionally, the decreasing effect of garlic at 25 g kg−1 diet on MDA values was only significant in liver. Protein carbonyl contents were only decreased significantly in muscle following garlic administration at 25 g kg−1 diet. Serum aspartate aminotransferase activity decreased significantly in carp that received 25 g kg−1 dietary garlic. Moreover, alkaline phosphatase activity decreased significantly in carp fed diets containing 25 and 50 g kg−1 garlic. On the other hand, garlic supplementation had no significant effect on gamma-glutamyl transferase activity and total protein, albumin, and creatinine concentrations. The results of the present study indicate that garlic powder has potential to decrease oxidative stress to some extent by reducing lipid and protein oxidation in some tissues of common carp.