Abstract
Lipid contents of the liver in rats refed the diet low in fat and either containing glucose or sucrose as a sole carbohydrate source after a fast for 2 days reached peaks after 3 days’ refeeding and then decreased. Lipid content of the liver for glucose as a sole carbohydrate source was less than that for sucrose. The supplementation with 5% or 10% safflower oil caused decrease in the liver lipid content of rats refed the diet either containing 69.9% glucose or a mixture of 34.9% glucose and 35.0% fructose. In the next experiments, the effects of various fatty acids on the lipid content of the liver of rats refed the diet either containing 69.9% glucose or a mixture of 34.9% glucose and 35.0% fructose were investigated. Of fatty acids supplemented, only linoleic acid resulted in preventing liver lipid accumulation. Whereas, saturated fatty acids or oleic acid had no effect on the fatty liver in fasted-refed rats. Thus, it is assumed that the formation of fatty liver in rats refed the diet low in fat and c...
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