Abstract
Effect of Dietary Enrichment with Curcumin on Collagen and Glycogen in Some Organs of The Obese Adult Male Albino Rat
Highlights
Obesity is an important health concern facing our world for a while (Jen et al, 2010)
Morphometric Result: 1.Area % of Collagen Fibers: The area % of the collagen fibers is significantly higher in the liver, lung and heart of obese rats when compared to the control group, while it shows significant reduction in the same organs of the curcumin treated groups when compared to obese rats (Table.2, Histogram .1)
2.Area % of periodic acid schief (PAS) +ve Material: The area % of the PAS+ve area is significantly higher in the liver and lung of obese rats when compared to the control group, while it shows significant reduction in the same organs of the curcumin treated groups when compared to obese rats
Summary
Obesity is an important health concern facing our world for a while (Jen et al, 2010) It has been listed as a risk factor for diseases like asthma. Curcumin has a poor bioavailability in vivo, which may interfere with its use as a therapeutic agent in certain conditions (Ireson et al, 2002). It is metabolized and excreted by the liver in a short time (Jurenka, 2009). Based on the previous reports; liver, lung and heart were selected to be studied in this article to investigate the effect of obesity on these vital organs and the possible protective role of curcumin
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More From: Egyptian Academic Journal of Biological Sciences, D. Histology & Histochemistry
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