Abstract
ObjectiveTo synthesise the evidence on the overall and differential effects of interventions based on diet and physical activity during pregnancy, primarily on gestational weight gain and maternal and offspring composite...
Highlights
Half of all women of childbearing age worldwide are overweight or obese.[1,2,3] Obesity and excessive gestational weight gain put mother and offspring at risk, both in pregnancy and in later life.[4,5,6] The resultant costs to the health service and society are considerable.[7 8]
Objective To synthesise the evidence on the overall and differential effects of interventions based on diet and physical activity during pregnancy, primarily on gestational weight gain and maternal and offspring composite outcomes, according to women’s body mass index, age, parity, ethnicity, and pre-existing medical condition; and secondarily on individual complications
Diet and physical activity based interventions consistently reduce gestational weight gain across various subgroups of women categorised by age, parity, body mass index, ethnicity, and pre-existing medical condition The reduction in odds of adverse maternal and offspring composite outcomes with diet and physical activity is not significant, and does not vary across various subgroups of women Interventions significantly lower the odds of caesarean section and have no effect on offspring outcomes in maternal and offspring (0.94, 0.83 to 1.08, I2=0%; 18 studies, 7981 women) composite outcomes were not statistically significant
Summary
Half of all women of childbearing age worldwide are overweight or obese.[1,2,3] Obesity and excessive gestational weight gain put mother and offspring at risk, both in pregnancy and in later life.[4,5,6] The resultant costs to the health service and society are considerable.[7 8]. These problems can be addressed by evidence synthesis using raw individual level data from relevant studies.[20 21]
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