Abstract
Effects of dibutyryl adenosine 3', 5'-cyclic monophosphate (db-cAMP) on glycolysis, oxygen uptake and protein synthesis were inves-tigated in unfertilized sea urchin eggs to examine the possible role of adenosine 3', 5'-cyclic monophosphate in the activation of cellular functions upon fertilization. Treatment of unfertilized eggs with 1 to 5 mM of db-cAMP caused activation of the glycolytic system but exerted no effect on oxygen uptake and protein synthesis. The influx of Ca2+ into the eggs, having been demonstrated upon fertilization, was not observed in unfertilized eggs when the eggs were treated with cAMP.
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