Effect of defibrase combined with ondansetron on cerebellar infarction vertigo

Abstract

Objective To observe the efficacy of defibrase combined with ondansetron on cerebellar infarction vertigo. Methods Fifty-eight patients with cerebellar infarction vertigo in the Department of Neurology of Gaozhou Hospital of Traditional Chinese Medicine from May 2017 to December 2018 were selected as the research objects. The patients were randomly divided into treatment group and control group, with 29 cases in each group.The treatment group was treated with defibrase combined with ondansetron treatment, an the control group was treated with Danshen injection, 7 days was a course.The therapeutic effect was observed on the 7th day after treatment, and the clinical efficacy was compared between the two groups. At the same time, the vertigo symptoms of the two groups were scored by the Vertigo Symptoms and Functional Assessment Scale, and the objective efficacy of defibrase combined with ondansetron in the treatment of cerebellar vertigo was evaluated. Results The effective rate of the treatment group reached 89.7% on the 7th day after taking medicine, and that of the control group was 65.5%.The effective rate of the treatment group was higher than that of the control group (P<0.05). The score of vertigo functional symptoms in the treatment group was significantly superior to that in the control group, and the difference was significant (P<0.05). Conclusions Defibrase combined with ondansetron is effective and safe for cerebellar infarction vertigo. Key words: Defibrase; Ondansetron; Cerebral infarction vertigo