Abstract
The effect of decreases in renal sympathetic nerve activity on renal tubular sodium reabsorption was examined in anesthetized dogs. Reflex decreases in renal sympathetic nerve activity were produced by left atrial distention and stellate ganglion stimulation. Both interventions produced significant decreases in directly recorded efferent renal sympathetic nerve activity of 42 and 36%, respectively. With renal perfusion pressure held constant, neither glomerular filtration rate nor renal blood flow were significantly altered, but significant and reversible increases in urine flow and sodium excretion occurred. These studies demonstrate that reflex decreases in efferent renal sympathetic nerve activity result in decreases in renal tubular sodium reabsorption without changes in renal hemodynamics.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
