Abstract
The finite element (FE) analysis is a highly promising tool to simulate the behaviour of bone. Skeletal FE models in clinical routine rely on the information about the geometry and bone mineral density distribution from quantitative computed tomography (CT) imaging systems. Several parameters in CT imaging have been reported to affect the accuracy of FE models. FE models of bone are exclusively developed in vitro under scanning conditions deviating from the clinical setting, resulting in variability of FE results (< 10%). Slice thickness and field of view had little effect on FE predicted bone behaviour (≤ 4%), while the reconstruction kernels showed to have a larger effect (≤ 20%). Due to large interscanner variations (≤ 20%), the translation from an experimental model into clinical reality is a critical step. Those variations are assumed to be mostly caused by different “black box” reconstruction kernels and the varying frequency of higher density voxels, representing cortical bone. Considering the low number of studies together with the significant effect of CT imaging on the finite element model outcome leading to high variability in the predicted behaviour, we propose further systematic research and validation studies, ideally preceding multicentre and longitudinal studies.
Highlights
The finite element (FE) analysis is a computer simulation method, originally developed to solve complex problems in civil and aeronautical engineering
This paper aims to discuss in detail the effect of computed tomography (CT) imaging, i.e., in situ versus in vitro scanning, calibration differences and intra- and interscanner variability, on the accuracy of FE modelling in bone
We showed that while quantitative computed tomography (QCT)-based FE models have a great potential for use in clinical routine, their in vivo results must be interpreted carefully, with special attention given to subject size, resolution and quality of CT-scan images, and especially when using multiple QCT imaging systems
Summary
The finite element (FE) analysis is a computer simulation method, originally developed to solve complex problems in civil and aeronautical engineering. Today, this method is widely applied in mathematics and many engineering fields. This method is widely applied in mathematics and many engineering fields In this numerical method, a large system is subdivided into a mesh of smaller and simpler parts, the so-called finite elements, through a discretisation process. Force or displacement boundary conditions are applied at each element’s nodes with a material model defined for the analysis domain. This information is used to assemble a large system of equations. Solving the local equations delivers model deformations and internal mechanical stresses
Sign-in/Register to view highlights & summary Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
