Abstract
Crossed-perfusions of homologous loci of the mesencephalic reticular formation were carried out on pairs of “encéphale isolé” cats in order to detect the possible secretion of a chemical substance mediating electrocortical synchronization and desynchronization. Special care was taken in quantitatively determining (i) the precise site and diffusion of perfusates in different brain stem structures by scintillographic radioactivity determination of a 14C-labeled cerebrospinal fluid used as perfusate solution; (ii) the spontaneous variations in the amount of electroencephalogram (EEG) synchrony by determining changes in concentration of delta EEG waves and amplitude of cortical recruiting responses; and (iii) possible variations in hydrodynamic function of the perfusion system reflected in changes in body temperature, electrocardiogram rate, and blood pressure. The results showed that perfusion of the tegmental mesencephalic reticular formation (with maximal radioactivity in the ipsilateral formation) with perfusate with possible desynchronizing properties significantly reduced the concentration of delta waves and the amplitude of recruiting responses under stable conditions of temperature, heart rate, and blood pressure.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
