Abstract
To evaluate the influence of 2.2mm clear corneal incision (CCI) features in surgically induced astigmatism (SIA) and higher-order aberrations (HOAs) after cataract surgery. Right eyes of 92 subjects receiving 2.2mm incision cataract surgery were involved. A total of 38 eyes were categorized as the intact incision group, and 54 eyes were the defective incision group. Pre- and postoperative (1month and 6months) corneal astigmatism and HOAs on anterior and posterior corneal surfaces, corneal volume, and corneal thickness (CT) were measured using Pentacam. The CCI features including incision length (IL), incision angles, distance from incision to central cornea (Dis-En/Ex), and CT at incision site were quantified using AS-OCT. The defective incision group showed shorter IL and larger incision angles [false discovery rate (FDR) - p<0.05]. Changes in CT at incision site were more pronounced for the defective incision group (FDR - p<0.05). Some SIA parameters were related to the certain specific CCI features, especially IL (FDR - p<0.05). Both groups exhibited significant increased 6mm posterior corneal tHOAs at 1month (Bonferroni corrected - p<0.01) and the defective incision group showed increased 6mm posterior tHOAs at 6months (Bonferroni corrected - p=0.023). There were characteristic correlations between Zernike terms and CCI features including IL, CT, Dis-En/Ex, and incision angles at 1month, especially over 6mm zone. The CCI deformities can affect corneal recovery and induce more HOAs at 1month postoperatively. Such effects became minor, but could persist until 6months. The IL combined with Angle-En/Ex was important factor influencing CCI integrity and corneal optical quality.
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